BTN3A1

Across TCGA patient cohorts, BTN3A1 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTN3A1-associated genes across cancer lineages are ASNS, 14-3-3_beta, and ACVRL1. Each is linked with BTN3A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both BTN3A1-to-partner and partner-to-BTN3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by BTN3A1-low versus BTN3A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTN3A1→partner) and Y-score (partner→BTN3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.483	+1.906	<.001	.015	3	3
SKCM	14-3-3_beta →	+0.169	+3.000	.022	.036	3	2
SKCM	ACVRL1 →	+0.162	+2.820	.042	.035	3	2
UCEC	FoxM1 →	+0.214	+3.169	.019	.018	3	2
UCEC	PCNA →	+0.260	+2.700	<.001	.005	3	2
UCEC	Shc_pY317 →	-0.116	-1.662	.030	.011	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

ASNS by BTN3A1 expression — UCEC

Explore this box plot interactively →