BTN3A1

Across TCGA cell cohorts, BTN3A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,872 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible BTN3A1-associated GO terms across cancer lineages are Antigen processing and presentation of endogenous peptide antigen via MHC class I, Antigen processing and presentation of endogenous antigen, and Antigen processing and presentation of peptide antigen via MHC class Ib. Each is linked with BTN3A1 in more than 16 cancer types. Because this analysis shows association rather than direction, both BTN3A1-to-partner and partner-to-BTN3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen processing and presentation of endogenous peptide antigen via MHC class I grouped by BTN3A1-low versus BTN3A1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BTN3A1→partner) and Y-score (partner→BTN3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Antigen processing and presentation of endogenous peptide antigen via MHC class I →	+0.275	+2.088	.001	.001	3	17
BREAST	Antigen processing and presentation of endogenous antigen →	+0.252	+1.561	<.001	<.001	3	15
BREAST	Antigen processing and presentation of peptide antigen via MHC class Ib →	+0.282	+1.818	<.001	<.001	3	15
SOFT_TISSUE	Antigen processing and presentation of peptide antigen via MHC class I →	+0.210	+1.845	<.001	<.001	3	15
BREAST	Antigen processing and presentation via MHC class Ib →	+0.290	+1.818	<.001	<.001	3	15
BLOOD_Lymphoma	Antigen processing and presentation of endogenous peptide antigen via MHC class Ib →	+0.225	+1.401	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,872 associations by consensus.

Antigen processing and presentation of endogenous peptide antigen via MHC class I by BTN3A1 expression — LIVER

Explore this box plot interactively →