BTN3A1

Across TCGA cell cohorts, BTN3A1 mutation is significantly associated with the RNA expression of many other genes, with 588 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BTN3A1-associated genes across cancer lineages are GCAT, EIF3L, and BMX. Each is linked with BTN3A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTN3A1-to-partner and partner-to-BTN3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GCAT grouped by BTN3A1-low versus BTN3A1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTN3A1→partner) and Y-score (partner→BTN3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GCAT →	+1.476	+3.364	<.001	.002	3	1
LARGE_INTESTINE	EIF3L →	+0.518	+3.237	.004	.003	3	1
LARGE_INTESTINE	BMX →	+0.172	+2.447	.002	.003	3	1
LARGE_INTESTINE	SEMA3G →	+1.018	+3.364	<.001	.002	3	1
LARGE_INTESTINE	FZD3 →	+0.854	+3.364	<.001	.002	3	1
LARGE_INTESTINE	RBM28 →	+0.562	+3.364	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 588 associations by consensus.

GCAT by BTN3A1 expression — LARGE_INTESTINE

Explore this box plot interactively →