BTN1A1

Across TCGA patient cohorts, BTN1A1 mutation is significantly associated with the RNA expression of many other genes, with 2,909 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTN1A1-associated genes across cancer lineages are SFXN4, MIR769, and ZNF280B. Each is linked with BTN1A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both BTN1A1-to-partner and partner-to-BTN1A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SFXN4 grouped by BTN1A1-low versus BTN1A1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTN1A1→partner) and Y-score (partner→BTN1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SFXN4 →	+0.609	+2.913	<.001	.001	3	3
SKCM	MIR769 →	+0.137	+2.186	.007	.009	3	3
UCEC	ZNF280B →	+0.624	+2.332	<.001	<.001	3	3
UCEC	NSMCE4A →	+0.479	+2.917	<.001	<.001	3	3
COAD	PSAT1P4 →	+0.308	+4.463	<.001	.002	3	3
UCEC	RMDN1 →	+0.355	+2.592	.003	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,909 associations by consensus.

SFXN4 by BTN1A1 expression — SKCM

Explore this box plot interactively →