Across TCGA cell cohorts, BTLA RNA expression is significantly associated with the go_rna of many other GO terms, with 1,582 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BTLA-associated GO terms across cancer lineages are Positive regulation of protein modification by small protein conjugation or removal, Regulation of type B pancreatic cell development, and mRNA cis splicing, via spliceosome. Each is linked with BTLA in more than 5 cancer types. Because this analysis shows association rather than direction, both BTLA-to-partner and partner-to-BTLA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BTLA→partner) and Y-score (partner→BTLA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of protein modification by small protein conjugation or removal →	+0.044	+0.052	<.001	<.001	3	6
BONE	Regulation of type B pancreatic cell development →	+0.154	+0.120	<.001	.005	3	5
LUNG_NSCLC_LUAD	mRNA cis splicing, via spliceosome →	+0.053	+0.046	.001	.006	3	5
PANCREAS	Positive regulation of post-translational protein modification →	+0.043	+0.052	<.001	<.001	3	5
PANCREAS	Regulation of stem cell population maintenance →	+0.039	+0.057	<.001	<.001	3	5
SKIN	Neurotransmitter uptake →	-0.114	-0.092	.002	.003	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,582 associations by consensus.

Exploration

BTLA survival (RNA) · tumor vs normal (RNA) · all BTLA data types