BTK

Across TCGA cell cohorts, BTK RNA expression is significantly associated with the RNA expression of many other genes, with 8,491 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BTK-associated genes across cancer lineages are NCKAP1L, SPI1, and NIBAN3. Each is linked with BTK in more than 7 cancer types. Because this analysis shows association rather than direction, both BTK-to-partner and partner-to-BTK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTK versus NCKAP1L in BLOOD_Myeloma, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTK→partner) and Y-score (partner→BTK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	NCKAP1L →	+2.753	+3.724	.001	<.001	3	8
BLOOD_Lymphoma	SPI1 →	+5.024	+5.587	<.001	<.001	3	6
BLOOD_Lymphoma	NIBAN3 →	+4.792	+5.244	<.001	<.001	3	6
BLOOD_Lymphoma	RASSF2 →	+3.323	+4.368	<.001	<.001	3	5
BLOOD_Myeloma	CD53 →	+2.804	+2.403	.001	.002	2	6
BLOOD_Myeloma	PLCG2 →	+3.090	+3.525	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,491 associations by consensus.

BTK vs NCKAP1L — BLOOD_Myeloma

Explore this scatter interactively →