BTG3

Across TCGA cell cohorts, BTG3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,395 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible BTG3-associated GO terms across cancer lineages are Regulation of protein ADP-ribosylation, Protein localization to nucleus, and Negative regulation of ERAD pathway. Each is linked with BTG3 in more than 8 cancer types. Because this analysis shows association rather than direction, both BTG3-to-partner and partner-to-BTG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein ADP-ribosylation grouped by BTG3-low versus BTG3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BTG3→partner) and Y-score (partner→BTG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of protein ADP-ribosylation →	+0.117	+1.233	<.001	.004	3	9
OESOPHAGUS	Protein localization to nucleus →	+0.066	+1.608	.002	.001	3	9
OVARY	Negative regulation of ERAD pathway →	+0.085	+0.954	<.001	.002	3	8
BREAST	Regulation of cytokinesis →	+0.052	+1.517	.002	.001	3	8
LUNG_SCLC	DNA synthesis involved in DNA replication →	+0.096	+0.940	.002	.001	3	8
BREAST	Regulation of mitotic sister chromatid separation →	+0.110	+1.289	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,395 associations by consensus.

Regulation of protein ADP-ribosylation by BTG3 expression — OVARY

Explore this box plot interactively →