BTG3

Across TCGA cell cohorts, BTG3 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BTG3-associated genes across cancer lineages are ZNF831, TAFA1, and CENPVL1. Each is linked with BTG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTG3-to-partner and partner-to-BTG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF831 grouped by BTG3-low versus BTG3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTG3→partner) and Y-score (partner→BTG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZNF831 →	+0.018	+4.273	<.001	.006	3	1
LARGE_INTESTINE	TAFA1 →	+0.410	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CENPVL1 →	+0.227	+4.095	<.001	.009	3	1
BLOOD_Leukemia	ASZ1 →	+0.145	+4.152	<.001	.009	3	1
BLOOD_Leukemia	SERPINA12 →	+0.059	+5.060	<.001	.001	3	1
BLOOD_Leukemia	TMEM114 →	+0.022	+4.539	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

ZNF831 by BTG3 expression — LARGE_INTESTINE

Explore this box plot interactively →