BTG3-AS1

Across TCGA pan-cancer cohorts, BTG3-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated BTG3-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher BTG3-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated BTG3-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, MESO, and ACC are the cancer types where BTG3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.425	0.237	<.001	100	view →
MESO	OS	Tertile	All	0.262	0.562	<.001	96	view →
ACC	DFS	Tertile	All	0.373	0.792	<.001	53	view →
LGG	OS	Median	All	0.375	0.535	<.001	50	view →
KIRP	DFS	Tertile	III,IV	0.429	0.785	.004	28	view →
LUAD	DFS	Tertile	III,IV	0.785	0.492	.010	25	view →
PCPG	DFS	Median	All	0.566	0.945	.003	19	view →
COAD	OS	Median	IV	0.298	0.663	.006	18	view →
LUSC	OS	Tertile	All	0.816	0.733	.014	13	view →
SKCM	OS	Tertile	All	0.266	0.580	.007	12	view →
LIHC	DFS	Quartile	All	0.358	0.523	.007	11	view →
KICH	OS	Quartile	III,IV	1.000	0.241	.020	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

BTG3-AS1–HNSC (DFS)

Open the HNSC breakdown →