BTG2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, BTG2 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated BTG2 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher BTG2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated BTG2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD and LSCC are the cancer types where BTG2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSTertileII,III,IV0.8160.391.0174view →
LSCCDFSMedianAll0.8540.671.0193view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

BTG2–LUAD (OS)

Kaplan–Meier survival curve for BTG2 mass-spec protein-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration