BTG2

Across TCGA patient cohorts, BTG2 mutation is significantly associated with the RNA expression of many other genes, with 2,245 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTG2-associated genes across cancer lineages are RNU6-1, RNY3P11, and MIR3146. Each is linked with BTG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTG2-to-partner and partner-to-BTG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1 grouped by BTG2-low versus BTG2-high in DLBC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTG2→partner) and Y-score (partner→BTG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	RNU6-1 →	+0.369	+2.234	.002	.009	3	2
HNSC	RNY3P11 →	+0.523	+5.505	<.001	.004	3	2
BLCA	MIR3146 →	+0.448	+3.506	.007	.005	3	2
BLCA	PPP1R26P3 →	+0.009	+4.444	<.001	.006	3	2
UCEC	NDUFAF5 →	+0.486	+2.397	<.001	.003	3	2
UCEC	CYB5B →	+0.486	+3.021	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,245 associations by consensus.

RNU6-1 by BTG2 expression — DLBC

Explore this box plot interactively →