BTG2

Across TCGA cell cohorts, BTG2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BTG2-associated genes across cancer lineages are SPEM1, NBPF4, and KRTAP10-2. Each is linked with BTG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTG2-to-partner and partner-to-BTG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPEM1 grouped by BTG2-low versus BTG2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTG2→partner) and Y-score (partner→BTG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SPEM1 →	+0.102	+3.192	<.001	.008	3	1
BLOOD_Lymphoma	NBPF4 →	+0.793	+3.956	.005	.002	3	1
BLOOD_Lymphoma	KRTAP10-2 →	+0.032	+3.342	<.001	.008	3	1
BLOOD_Lymphoma	LRRC72 →	+0.021	+4.247	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SPEM1 by BTG2 expression — BLOOD_Lymphoma

Explore this box plot interactively →