BTG1

Across TCGA cell cohorts, BTG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,954 significant associations in total. BONE shows the largest number of these associations.

The most reproducible BTG1-associated GO terms across cancer lineages are Positive regulation of endothelial cell differentiation, Positive regulation of epithelial cell differentiation, and Endoplasmic reticulum to cytosol transport. Each is linked with BTG1 in more than 12 cancer types. Because this analysis shows association rather than direction, both BTG1-to-partner and partner-to-BTG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of endothelial cell differentiation grouped by BTG1-low versus BTG1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BTG1→partner) and Y-score (partner→BTG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of endothelial cell differentiation →	+0.239	+1.082	<.001	<.001	3	13
LUNG_SCLC	Positive regulation of epithelial cell differentiation →	+0.141	+0.894	<.001	.002	3	11
LUNG_NSCLC_LUAD	Endoplasmic reticulum to cytosol transport →	+0.081	+1.063	.001	<.001	3	10
LUNG_NSCLC_LUAD	Retrograde protein transport, ER to cytosol →	+0.081	+1.063	.001	<.001	3	10
BONE	XMP metabolic process →	-0.157	-1.598	<.001	<.001	3	10
BONE	XMP biosynthetic process →	-0.157	-1.598	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,954 associations by consensus.

Positive regulation of endothelial cell differentiation by BTG1 expression — PANCREAS

Explore this box plot interactively →