BTG1

Across TCGA cell cohorts, BTG1 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BTG1-associated genes across cancer lineages are OR1E2, OR11H1, and CRNN. Each is linked with BTG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTG1-to-partner and partner-to-BTG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1E2 grouped by BTG1-low versus BTG1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTG1→partner) and Y-score (partner→BTG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR1E2 →	+0.012	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	OR11H1 →	+0.036	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	CRNN →	+0.259	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	GPR119 →	+0.022	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR8J3 →	+0.023	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	CCL11 →	+0.028	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

OR1E2 by BTG1 expression — BLOOD_Lymphoma

Explore this box plot interactively →