BTF3L4P4

Across TCGA pan-cancer cohorts, BTF3L4P4 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of BTF3L4P4’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where BTF3L4P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BTF3L4P4 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

UCEC, HNSC, and THCA are the cancer types where BTF3L4P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BTF3L4P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	+0.420	.013	2	view →
HNSC	All	II,III,IV	+0.015	.041	2	view →
THCA	All	All	−0.013	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

BTF3L4P4–UCEC

Open the UCEC breakdown →