BTF3L4

Across TCGA patient cohorts, BTF3L4 protein abundance is significantly associated with the RNA expression of many other genes, with 8,674 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BTF3L4-associated genes across cancer lineages are CSF3R, FCGR3B, and ADGRG3. Each is linked with BTF3L4 in more than 4 cancer types. Because this analysis shows association rather than direction, both BTF3L4-to-partner and partner-to-BTF3L4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTF3L4 versus CSF3R in COAD, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTF3L4→partner) and Y-score (partner→BTF3L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CSF3R →	-1.201	-0.340	<.001	<.001	3	5
LSCC	FCGR3B →	-1.872	-0.305	<.001	<.001	3	5
PDAC	ADGRG3 →	-1.146	-0.363	<.001	<.001	3	5
BRCA	MRPL37 →	+0.595	+0.280	<.001	.001	3	5
LUAD	NRDC →	+0.386	+0.211	<.001	<.001	3	5
UCEC	MEFV →	-0.732	-0.329	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,674 associations by consensus.

BTF3L4 vs CSF3R — COAD

Explore this scatter interactively →