BTF3L4

Across TCGA patient cohorts, BTF3L4 mutation is significantly associated with the RNA expression of many other genes, with 338 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTF3L4-associated genes across cancer lineages are RN7SL813P, DNAJB8-AS1, and TRAV28. Each is linked with BTF3L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTF3L4-to-partner and partner-to-BTF3L4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL813P grouped by BTF3L4-low versus BTF3L4-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTF3L4→partner) and Y-score (partner→BTF3L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL813P →	+0.276	+5.688	<.001	<.001	3	1
CESC	DNAJB8-AS1 →	+0.027	+4.760	.003	.003	3	1
CESC	TRAV28 →	+0.705	+4.193	.001	.009	3	1
CESC	AHCYP7 →	+0.060	+4.409	<.001	.006	3	1
CESC	MIR8053 →	+0.379	+5.342	<.001	.002	3	1
UCEC	CWC15 →	+0.513	+3.202	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 338 associations by consensus.

RN7SL813P by BTF3L4 expression — CESC

Explore this box plot interactively →