BTF3L4

Across TCGA patient cohorts, BTF3L4 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTF3L4-associated genes across cancer lineages are p27_pT157, Rad50, and Bim. Each is linked with BTF3L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTF3L4-to-partner and partner-to-BTF3L4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p27_pT157 grouped by BTF3L4-low versus BTF3L4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTF3L4→partner) and Y-score (partner→BTF3L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT157 →	-0.065	-3.130	.026	.019	3	1
UCEC	Rad50 →	-0.277	-2.321	.022	.035	3	1
UCEC	Bim →	-0.279	-2.321	.034	.035	2	1
UCEC	CD49b →	-0.295	-2.980	.038	.036	2	1
UCEC	Di-Ras3 →	-0.149	-2.321	.045	.035	2	1
UCEC	MEK1 →	+0.552	+3.459	.002	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

p27_pT157 by BTF3L4 expression — UCEC

Explore this box plot interactively →