BTF3

Across TCGA patient cohorts, BTF3 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,679 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BTF3-associated proteins across cancer lineages are MSH3, NPM1, and SCAMP1. Each is linked with BTF3 in more than 6 cancer types. Because this analysis shows association rather than direction, both BTF3-to-partner and partner-to-BTF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTF3 versus MSH3 in BRCA, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BTF3→partner) and Y-score (partner→BTF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MSH3 →	+0.391	+0.674	<.001	<.001	3	7
OV	NPM1 →	+0.454	+0.415	<.001	.005	3	6
LSCC	SCAMP1 →	+0.369	+0.651	<.001	<.001	3	6
LSCC	NLN →	+0.398	+0.459	<.001	<.001	3	5
LSCC	RRBP1 →	-0.490	-0.574	<.001	<.001	3	5
LSCC	HSPA4 →	+0.258	+0.435	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,679 associations by consensus.

BTF3 vs MSH3 — BRCA

Explore this scatter interactively →