BTF3

Across TCGA patient cohorts, BTF3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,747 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BTF3-associated genes across cancer lineages are CSF3R, FCGR3B, and CXCR2. Each is linked with BTF3 in more than 5 cancer types. Because this analysis shows association rather than direction, both BTF3-to-partner and partner-to-BTF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTF3 versus CSF3R in HNSC, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTF3→partner) and Y-score (partner→BTF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CSF3R →	-1.155	-0.483	<.001	<.001	3	6
LSCC	FCGR3B →	-1.486	-0.294	<.001	<.001	3	6
LSCC	CXCR2 →	-1.033	-0.258	<.001	<.001	3	6
PDAC	ADGRG3 →	-1.143	-0.386	<.001	<.001	3	6
LSCC	FCAR →	-0.708	-0.304	<.001	<.001	3	6
UCEC	METAP2 →	+0.539	+0.288	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,747 associations by consensus.

BTF3 vs CSF3R — HNSC

Explore this scatter interactively →