BTD

Across TCGA cell cohorts, BTD RNA expression is significantly associated with the go_rna of many other GO terms, with 5,393 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BTD-associated GO terms across cancer lineages are Biotin metabolic process, Protein oxidation, and Protein targeting to lysosome involved in chaperone-mediated autophagy. Each is linked with BTD in more than 17 cancer types. Because this analysis shows association rather than direction, both BTD-to-partner and partner-to-BTD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Biotin metabolic process grouped by BTD-low versus BTD-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BTD→partner) and Y-score (partner→BTD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Biotin metabolic process →	+0.163	+1.223	<.001	<.001	3	18
BONE	Protein oxidation →	+1.198	+1.159	<.001	<.001	3	12
BLOOD_Lymphoma	Protein targeting to lysosome involved in chaperone-mediated autophagy →	+0.215	+1.154	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of natural killer cell differentiation →	+0.368	+1.732	.002	<.001	3	10
BLOOD_Lymphoma	Protein targeting to lysosome →	+0.049	+0.690	<.001	<.001	3	10
BONE	Positive regulation of focal adhesion assembly →	+0.187	+1.266	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,393 associations by consensus.

Biotin metabolic process by BTD expression — BLOOD_Myeloma

Explore this box plot interactively →