Across TCGA patient cohorts, BTBD9 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible BTBD9-associated genes across cancer lineages are MEK1, Rad50, and JNK2. Each is linked with BTBD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTBD9-to-partner and partner-to-BTBD9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD9→partner) and Y-score (partner→BTBD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.278	+2.115	.042	.017	3	2
SKCM	Rad50 →	-0.278	-3.309	.045	.009	3	2
UCEC	JNK2 →	+0.247	+2.611	<.001	.005	3	1
UCEC	Ku80 →	+0.205	+1.778	.020	.008	3	1
UCEC	PKC-a_pS657 →	+0.316	+1.428	.027	.029	3	1
UCEC	PKC-a →	+0.353	+2.472	.020	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

BTBD9 survival (RNA) · tumor vs normal (RNA) · all BTBD9 data types