Across TCGA patient cohorts, BTBD8 protein abundance is significantly associated with the RNA expression of many other genes, with 9,150 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BTBD8-associated genes across cancer lineages are SCCPDH, NBR1, and TATDN3. Each is linked with BTBD8 in more than 3 cancer types. Because this analysis shows association rather than direction, both BTBD8-to-partner and partner-to-BTBD8 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD8→partner) and Y-score (partner→BTBD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SCCPDH →	+1.146	+0.624	<.001	.001	3	4
BRCA	NBR1 →	+0.607	+0.535	<.001	.001	3	4
BRCA	TATDN3 →	+0.518	+0.644	<.001	<.001	3	4
PDAC	AMY2B →	+1.832	+0.374	.002	.001	3	3
GBM	NPY →	+1.187	+0.389	<.001	<.001	3	3
GBM	CDKL2 →	+0.952	+0.658	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,150 associations by consensus.

Exploration

BTBD8 survival (RNA) · tumor vs normal (RNA) · all BTBD8 data types