Across TCGA patient cohorts, BTBD8 mutation is significantly associated with the RNA expression of many other genes, with 1,914 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTBD8-associated genes across cancer lineages are OR5D3P, BLOC1S2P1, and NDUFB6. Each is linked with BTBD8 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTBD8-to-partner and partner-to-BTBD8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD8→partner) and Y-score (partner→BTBD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR5D3P →	+0.113	+6.917	<.001	<.001	3	2
COAD	BLOC1S2P1 →	+0.443	+5.080	<.001	.008	3	2
UCEC	NDUFB6 →	+0.429	+2.584	.005	.001	3	2
SKCM	RPL5P7 →	+0.025	+2.270	.009	.007	3	2
UCEC	CLPP →	+0.479	+3.470	.003	.002	3	2
UCEC	GRHPR →	+0.364	+2.633	.009	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,914 associations by consensus.

Exploration

BTBD8 survival (RNA) · tumor vs normal (RNA) · all BTBD8 data types