BTBD7

Across TCGA patient cohorts, BTBD7 mutation is significantly associated with the RNA expression of many other genes, with 3,652 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTBD7-associated genes across cancer lineages are VN1R88P, RNU6-764P, and CCDC51. Each is linked with BTBD7 in more than 3 cancer types. Because this analysis shows association rather than direction, both BTBD7-to-partner and partner-to-BTBD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R88P grouped by BTBD7-low versus BTBD7-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD7→partner) and Y-score (partner→BTBD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	VN1R88P →	+0.380	+4.099	.002	.002	3	3
BLCA	RNU6-764P →	+0.196	+3.925	<.001	.001	3	3
UCEC	CCDC51 →	+0.335	+1.469	.003	<.001	3	3
UCEC	RNF34 →	+0.241	+1.523	.003	<.001	3	3
UCEC	MNAT1 →	+0.366	+1.469	.001	<.001	3	3
UCEC	MRPS23 →	+0.342	+1.645	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,652 associations by consensus.

VN1R88P by BTBD7 expression — LUAD

Explore this box plot interactively →