BTBD3

Across TCGA patient cohorts, BTBD3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,128 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTBD3-associated genes across cancer lineages are NHP2P1, HDDC2, and WNT1. Each is linked with BTBD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTBD3-to-partner and partner-to-BTBD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTBD3 versus NHP2P1 in LUAD, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD3→partner) and Y-score (partner→BTBD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NHP2P1 →	-0.774	-0.568	.002	.002	3	1
LUAD	HDDC2 →	+0.494	+0.513	.004	.003	3	1
LUAD	WNT1 →	-0.354	-0.584	.003	<.001	3	1
LUAD	TMX4 →	-0.394	-0.444	.004	.002	3	1
LUAD	NUDT15 →	+0.573	+0.489	.002	.003	3	1
LUAD	ABHD17C →	+0.746	+0.398	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,128 associations by consensus.

BTBD3 vs NHP2P1 — LUAD

Explore this scatter interactively →