BTBD3

Across TCGA patient cohorts, BTBD3 mutation is significantly associated with the RNA expression of many other genes, with 4,536 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTBD3-associated genes across cancer lineages are LINC02654, RN7SKP256, and RN7SKP171. Each is linked with BTBD3 in more than 3 cancer types. Because this analysis shows association rather than direction, both BTBD3-to-partner and partner-to-BTBD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02654 grouped by BTBD3-low versus BTBD3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD3→partner) and Y-score (partner→BTBD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC02654 →	+0.679	+4.824	<.001	.002	3	4
HNSC	RN7SKP256 →	+0.209	+6.468	<.001	.001	3	3
HNSC	RN7SKP171 →	+0.150	+6.221	<.001	.001	3	3
UCEC	SEC13 →	+0.435	+2.146	<.001	<.001	3	3
UCEC	SNRNP25 →	+0.452	+2.490	<.001	<.001	3	3
UCEC	PTTG1 →	+0.563	+1.688	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,536 associations by consensus.

LINC02654 by BTBD3 expression — COAD

Explore this box plot interactively →