BTBD2

Across TCGA patient cohorts, BTBD2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,608 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BTBD2-associated genes across cancer lineages are IKZF3, IFT22, and TXNDC17. Each is linked with BTBD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both BTBD2-to-partner and partner-to-BTBD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTBD2 versus IKZF3 in BRCA, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD2→partner) and Y-score (partner→BTBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IKZF3 →	-1.017	-0.358	<.001	<.001	3	5
CCRCC	IFT22 →	+0.483	+0.272	<.001	<.001	3	4
UCEC	TXNDC17 →	+0.832	+0.252	.001	<.001	3	4
UCEC	UBL5 →	+0.540	+0.142	.001	.001	3	4
HNSC	LY9 →	-0.508	-0.269	<.001	<.001	3	4
BRCA	DTNB-AS1 →	-0.894	-0.333	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,608 associations by consensus.

BTBD2 vs IKZF3 — BRCA

Explore this scatter interactively →