BTBD2

Across TCGA cell cohorts, BTBD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,157 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BTBD2-associated GO terms across cancer lineages are Energy coupled proton transmembrane transport, against electrochemical gradient, Electron transport coupled proton transport, and Positive regulation of anaphase-promoting complex-dependent catabolic process. Each is linked with BTBD2 in more than 15 cancer types. Because this analysis shows association rather than direction, both BTBD2-to-partner and partner-to-BTBD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy coupled proton transmembrane transport, against electrochemical gradient grouped by BTBD2-low versus BTBD2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD2→partner) and Y-score (partner→BTBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.121	+1.272	<.001	<.001	3	16
OESOPHAGUS	Electron transport coupled proton transport →	+0.121	+1.272	<.001	<.001	3	16
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.169	+1.328	<.001	<.001	3	16
BONE	Transcription pausing by RNA polymerase II →	+0.184	+1.158	<.001	<.001	3	15
BONE	Negative regulation of transcription initiation by RNA polymerase II →	+0.123	+0.952	<.001	.002	3	15
UPPER_AERODIGESTIVE_TRACT	Cytoplasm protein quality control →	+0.127	+0.972	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,157 associations by consensus.

Energy coupled proton transmembrane transport, against electrochemical gradient by BTBD2 expression — OESOPHAGUS

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