BTBD16

Across TCGA patient cohorts, BTBD16 mutation is significantly associated with the RNA expression of many other genes, with 3,029 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTBD16-associated genes across cancer lineages are RNA5SP436, RNU6-236P, and MIR629. Each is linked with BTBD16 in more than 2 cancer types. Because this analysis shows association rather than direction, both BTBD16-to-partner and partner-to-BTBD16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP436 grouped by BTBD16-low versus BTBD16-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD16→partner) and Y-score (partner→BTBD16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP436 →	+0.272	+2.867	<.001	<.001	3	3
CESC	RNU6-236P →	+0.431	+5.418	<.001	.005	3	2
CESC	MIR629 →	+0.461	+5.418	<.001	.005	3	2
READ	RPL35AP30 →	+0.294	+5.421	<.001	.005	3	2
UCEC	FAM168B →	+0.519	+2.230	.002	.006	3	2
UCEC	BUB3 →	+0.480	+2.070	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,029 associations by consensus.

RNA5SP436 by BTBD16 expression — UCEC

Explore this box plot interactively →