BTBD16

Across TCGA cell cohorts, BTBD16 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BTBD16-associated genes across cancer lineages are SLC22A12, TRIM60, and ETDC. Each is linked with BTBD16 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTBD16-to-partner and partner-to-BTBD16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC22A12 grouped by BTBD16-low versus BTBD16-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD16→partner) and Y-score (partner→BTBD16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	SLC22A12 →	+0.006	+5.781	<.001	.001	3	1
BLOOD_Lymphoma	TRIM60 →	+0.345	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	ETDC →	+0.556	+5.209	<.001	.005	3	1
LARGE_INTESTINE	AVP →	+0.068	+4.217	<.001	.001	3	1
LARGE_INTESTINE	MAGEB4 →	+0.019	+5.000	<.001	<.001	3	1
LARGE_INTESTINE	DAZ1 →	+0.848	+3.758	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

SLC22A12 by BTBD16 expression — BREAST

Explore this box plot interactively →