BTBD10

Across TCGA patient cohorts, BTBD10 protein abundance is significantly associated with the RNA expression of many other genes, with 3,406 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BTBD10-associated genes across cancer lineages are RRN3P2, GEM, and TRAJ8. Each is linked with BTBD10 in more than 2 cancer types. Because this analysis shows association rather than direction, both BTBD10-to-partner and partner-to-BTBD10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTBD10 versus RRN3P2 in HNSC, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD10→partner) and Y-score (partner→BTBD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RRN3P2 →	-0.332	-0.331	.003	.008	3	3
LSCC	GEM →	-0.818	-0.264	.001	<.001	3	3
HNSC	TRAJ8 →	-1.223	-0.309	.002	.001	3	3
PDAC	WWTR1-IT1 →	-0.849	-0.519	<.001	.001	3	3
HNSC	DOK5 →	-0.514	-0.303	.001	<.001	3	2
HNSC	PPP1R16B →	-0.831	-0.276	.003	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,406 associations by consensus.

BTBD10 vs RRN3P2 — HNSC

Explore this scatter interactively →