BTBD10

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BTBD10 mutation is significantly associated with the RNA expression of many other genes, with 1,827 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTBD10-associated genes across cancer lineages are RN7SL134P, RNA5SP411, and RNU6-273P. Each is linked with BTBD10 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTBD10-to-partner and partner-to-BTBD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by BTBD10-low versus BTBD10-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD10→partner) and Y-score (partner→BTBD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL134P →+0.107+3.874.002.00632
UCECRNA5SP411 →+1.735+3.094<.001<.00132
LUADRNU6-273P →+0.506+5.523<.001.00132
LUADF8A2 →+0.043+3.926<.001.00532
CESCSNORA36A →+0.380+3.653<.001.00932
UCECSLC25A4 →+0.634+3.258<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,827 associations by consensus.

RN7SL134P by BTBD10 expression — CESC

Box plot of RN7SL134P in BTBD10-low vs BTBD10-high samples in CESC.

Explore this box plot interactively →

Exploration