BTBD10

Across TCGA cell cohorts, BTBD10 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BTBD10-associated genes across cancer lineages are MMP26, CA6, and SOX3. Each is linked with BTBD10 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTBD10-to-partner and partner-to-BTBD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by BTBD10-low versus BTBD10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD10→partner) and Y-score (partner→BTBD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MMP26 →	+0.033	+3.217	<.001	.006	3	1
BLOOD_Lymphoma	CA6 →	+0.667	+3.956	<.001	.002	3	1
BLOOD_Lymphoma	SOX3 →	+0.357	+3.342	<.001	.008	3	1
BLOOD_Lymphoma	LCE2B →	+0.030	+3.342	<.001	.008	3	1
BLOOD_Lymphoma	HTR3D →	+0.010	+4.247	<.001	.004	3	1
BLOOD_Lymphoma	FRRS1L →	+0.057	+3.584	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MMP26 by BTBD10 expression — LARGE_INTESTINE

Explore this box plot interactively →