BTBD1

Across TCGA patient cohorts, BTBD1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,763 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible BTBD1-associated genes across cancer lineages are CYSTM1, KRTAP5-10, and ITGB1BP1. Each is linked with BTBD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTBD1-to-partner and partner-to-BTBD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTBD1 versus CYSTM1 in PDAC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD1→partner) and Y-score (partner→BTBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CYSTM1 →	-0.690	-0.226	.001	.006	3	2
UCEC	KRTAP5-10 →	-0.793	-0.414	<.001	<.001	3	2
LSCC	ITGB1BP1 →	+0.286	+0.219	.003	.002	3	2
PDAC	SLC9A4 →	-1.477	-0.246	.002	.002	3	2
UCEC	CTSLP3 →	-0.563	-0.279	.001	.002	3	2
HNSC	STC2 →	+1.072	+0.499	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,763 associations by consensus.

BTBD1 vs CYSTM1 — PDAC

Explore this scatter interactively →