BTBD1

Across TCGA patient cohorts, BTBD1 mutation is significantly associated with the RNA expression of many other genes, with 932 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTBD1-associated genes across cancer lineages are SCARNA21B, MIR920, and OR10R3P. Each is linked with BTBD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTBD1-to-partner and partner-to-BTBD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCARNA21B grouped by BTBD1-low versus BTBD1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD1→partner) and Y-score (partner→BTBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	SCARNA21B →	+0.476	+5.039	<.001	.008	3	2
LIHC	MIR920 →	+0.487	+5.268	<.001	.006	3	2
SKCM	OR10R3P →	+0.026	+5.810	<.001	<.001	3	2
SKCM	SDHDP5 →	+0.123	+3.817	<.001	.004	3	2
BLCA	MIR6737 →	+0.467	+6.147	<.001	.002	3	2
STAD	MIR4276 →	+0.474	+5.366	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 932 associations by consensus.

SCARNA21B by BTBD1 expression — READ

Explore this box plot interactively →