BTAF1

Across TCGA pan-cancer cohorts, BTAF1 Mutation is linked to patient survival in 9 of 34 cancer types, making it a survival-associated BTAF1 data layer compared with 26 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher BTAF1 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated BTAF1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, READ, and ESCA are the cancer types where BTAF1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.841	0.618	.002	34	view →
READ	OS	Median	III,IV	0.289	0.932	<.001	15	view →
ESCA	OS	Median	IV	0.095	0.512	.008	12	view →
LUAD	OS	Median	III,IV	0.199	0.688	<.001	12	view →
CESC	DFS	Median	IV	0.147	0.545	.008	6	view →
SCLC	OS	Median	All	0.082	0.653	.002	6	view →
LUSC	DFS	Median	II,III,IV	0.199	0.748	.006	6	view →
LIHC	DFS	Median	II,III,IV	0.113	0.431	.011	6	view →
SKCM	OS	Median	III,IV	0.230	0.721	.004	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

BTAF1–UCEC (DFS)

Open the UCEC breakdown →