BTAF1

Across TCGA pan-cancer cohorts, BTAF1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated BTAF1 data layer compared with 26 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher BTAF1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated BTAF1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

LSCC, CCRCC, and GBM are the cancer types where BTAF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.831	0.534	.003	44	view →
CCRCC	OS	Median	III,IV	0.695	0.942	.019	8	view →
GBM	DFS	Median	All	0.415	0.233	.042	5	view →
LUAD	DFS	Quartile	II,III,IV	0.217	0.781	.011	4	view →
UCEC	DFS	Tertile	II,III,IV	0.920	0.488	.041	4	view →
HNSC	DFS	Median	IV	0.328	0.889	.014	4	view →
PDAC	DFS	Tertile	II,III,IV	0.404	0.181	.043	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

BTAF1–LSCC (DFS)

Open the LSCC breakdown →