BTAF1

Across TCGA pan-cancer cohorts, BTAF1 mass-spec protein differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of BTAF1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where BTAF1 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types BTAF1 is over-expressed in tumor.

HNSC, CCRCC, and LSCC are the cancer types where BTAF1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BTAF1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.347	<.001	12	view →
CCRCC	Female	All	+0.174	<.001	10	view →
LSCC	Female	III,IV	+0.410	<.001	9	view →
LUAD	Female	All	+0.166	<.001	9	view →
COAD	Female	II,III,IV	+0.179	.003	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

BTAF1–HNSC

Open the HNSC breakdown →