BTAF1

Across TCGA patient cohorts, BTAF1 mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTAF1-associated genes across cancer lineages are Cyclin-E2, 4E-BP1, and C-Raf. Each is linked with BTAF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both BTAF1-to-partner and partner-to-BTAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-E2 grouped by BTAF1-low versus BTAF1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTAF1→partner) and Y-score (partner→BTAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cyclin-E2 →	+0.141	+2.190	.026	.033	3	3
COAD	4E-BP1 →	+0.291	+3.169	.003	.018	3	3
COAD	C-Raf →	+0.204	+3.467	.001	.002	3	3
STAD	FASN →	+0.537	+3.185	.005	.009	3	2
STAD	JNK_pT183_Y185 →	-0.172	-2.979	.001	.033	3	2
STAD	PCNA →	+0.356	+3.321	.008	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Cyclin-E2 by BTAF1 expression — STAD

Explore this box plot interactively →