BTAF1

Across TCGA cell cohorts, BTAF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,144 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BTAF1-associated GO terms across cancer lineages are Negative regulation of binding, Heterochromatin formation, and Subtelomeric heterochromatin formation. Each is linked with BTAF1 in more than 17 cancer types. Because this analysis shows association rather than direction, both BTAF1-to-partner and partner-to-BTAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of binding grouped by BTAF1-low versus BTAF1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BTAF1→partner) and Y-score (partner→BTAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of binding →	+0.133	+0.885	<.001	<.001	3	18
BONE	Heterochromatin formation →	+0.089	+1.248	<.001	<.001	3	17
BONE	Subtelomeric heterochromatin formation →	+0.128	+0.997	<.001	<.001	3	17
BONE	Negative regulation of telomere maintenance →	+0.082	+1.070	<.001	<.001	3	17
LUNG_SCLC	Regulation of maintenance of sister chromatid cohesion →	+0.152	+0.777	<.001	<.001	3	17
LUNG_SCLC	Regulation of maintenance of mitotic sister chromatid cohesion →	+0.152	+0.777	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,144 associations by consensus.

Negative regulation of binding by BTAF1 expression — LUNG_SCLC

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