BTAF1

Across TCGA cell cohorts, BTAF1 mutation is significantly associated with the RNA expression of many other genes, with 412 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BTAF1-associated genes across cancer lineages are CYP26C1, EFCAB1, and TEKT1. Each is linked with BTAF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both BTAF1-to-partner and partner-to-BTAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYP26C1 grouped by BTAF1-low versus BTAF1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTAF1→partner) and Y-score (partner→BTAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CYP26C1 →	+0.062	+3.369	<.001	.002	3	3
BLOOD_Lymphoma	EFCAB1 →	+0.147	+3.857	<.001	.003	3	2
SKIN	TEKT1 →	+0.072	+3.345	<.001	.007	3	2
SKIN	ARRDC5 →	+0.017	+4.669	<.001	<.001	3	2
LARGE_INTESTINE	CR2 →	+0.581	+3.184	.003	.007	3	2
LARGE_INTESTINE	FKBPL →	+0.480	+3.169	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 412 associations by consensus.

CYP26C1 by BTAF1 expression — BLOOD_Leukemia

Explore this box plot interactively →