BSX

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BSX RNA expression is significantly associated with the go_rna of many other GO terms, with 386 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible BSX-associated GO terms across cancer lineages are Regulation of post-translational protein modification, Negative regulation of cilium assembly, and Protein polyubiquitination. Each is linked with BSX in more than 2 cancer types. Because this analysis shows association rather than direction, both BSX-to-partner and partner-to-BSX results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BSX→partner) and Y-score (partner→BSX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCRegulation of post-translational protein modification →+0.037+0.538.001.00433
LUNG_SCLCNegative regulation of cilium assembly →+0.090+0.688<.001.00133
LUNG_SCLCProtein polyubiquitination →+0.029+0.519<.001.00633
OVARYUreteric bud development →-0.087-0.031.001.00733
LUNG_SCLCFibroblast growth factor receptor signaling pathway →-0.076-0.521.003.00533
OVARYPositive regulation of stress-activated protein kinase signaling cascade →+0.092+0.032.007.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 386 associations by consensus.

Exploration