Across TCGA cell cohorts, BSX mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BSX-associated genes across cancer lineages are ITGAD, PRAMEF20, and OR5V1. Each is linked with BSX in more than 1 cancer types. Because this analysis shows association rather than direction, both BSX-to-partner and partner-to-BSX results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BSX→partner) and Y-score (partner→BSX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ITGAD →	+0.018	+4.510	<.001	.001	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	OR5V1 →	+0.008	+4.437	<.001	.004	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.022	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR10G7 →	+0.016	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	LCE1F →	+0.151	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

BSX survival (RNA) · tumor vs normal (RNA) · all BSX data types