BST1

Across TCGA patient cohorts, BST1 mutation is significantly associated with the RNA expression of many other genes, with 2,228 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BST1-associated genes across cancer lineages are NIP7P1, TRDV1, and LINC01017. Each is linked with BST1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BST1-to-partner and partner-to-BST1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NIP7P1 grouped by BST1-low versus BST1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BST1→partner) and Y-score (partner→BST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	NIP7P1 →	+0.071	+4.618	<.001	.005	3	2
UCEC	TRDV1 →	+0.699	+2.426	<.001	.003	3	2
CESC	LINC01017 →	+0.085	+5.342	<.001	.002	3	1
CESC	PYDC2 →	+0.113	+5.342	<.001	.002	3	1
CESC	FRG2GP →	+0.050	+4.539	.008	.008	3	1
CESC	MIR4305 →	+0.277	+4.669	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,228 associations by consensus.

NIP7P1 by BST1 expression — BLCA

Explore this box plot interactively →