BSPRY

Across TCGA cell cohorts, BSPRY RNA expression is significantly associated with the go_rna of many other GO terms, with 4,361 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible BSPRY-associated GO terms across cancer lineages are Response to molecule of fungal origin, Cellular response to molecule of fungal origin, and Positive regulation of endothelial cell development. Each is linked with BSPRY in more than 12 cancer types. Because this analysis shows association rather than direction, both BSPRY-to-partner and partner-to-BSPRY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to molecule of fungal origin grouped by BSPRY-low versus BSPRY-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BSPRY→partner) and Y-score (partner→BSPRY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Response to molecule of fungal origin →	+1.610	+2.462	.001	.002	3	13
LUNG_NSCLC_LUSC	Cellular response to molecule of fungal origin →	+1.610	+2.462	.001	.002	3	13
BREAST	Positive regulation of endothelial cell development →	+0.321	+2.630	<.001	<.001	3	12
BREAST	Positive regulation of establishment of endothelial barrier →	+0.321	+2.630	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Serotonin secretion →	+1.882	+2.907	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Serotonin production involved in inflammatory response →	+1.882	+2.907	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,361 associations by consensus.

Response to molecule of fungal origin by BSPRY expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →