BSDC1

Across TCGA pan-cancer cohorts, BSDC1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated BSDC1 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher BSDC1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated BSDC1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, HNSC, and PDAC are the cancer types where BSDC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	1.000	0.458	<.001	40	view →
HNSC	DFS	Median	All	0.881	0.668	<.001	33	view →
PDAC	OS	Tertile	IV	0.414	0.973	.024	6	view →
LSCC	OS	Tertile	All	0.822	0.969	.010	5	view →
LUAD	OS	Tertile	II,III,IV	0.808	0.507	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

BSDC1–UCEC (DFS)

Open the UCEC breakdown →