BSDC1

Across TCGA patient cohorts, BSDC1 mutation is significantly associated with the RNA expression of many other genes, with 1,491 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BSDC1-associated genes across cancer lineages are RNA5SP250, DLGAP5P1, and RN7SL362P. Each is linked with BSDC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both BSDC1-to-partner and partner-to-BSDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP250 grouped by BSDC1-low versus BSDC1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BSDC1→partner) and Y-score (partner→BSDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP250 →	+0.213	+5.327	<.001	.001	3	3
LGG	DLGAP5P1 →	+0.084	+7.977	<.001	.007	3	2
HNSC	RN7SL362P →	+0.144	+4.015	<.001	.003	3	2
SKCM	RNU5B-3P →	+0.331	+3.451	<.001	<.001	3	2
UCEC	RPL17P50 →	+0.435	+2.108	.005	.003	3	2
UCEC	DYNLT3P2 →	+0.429	+2.918	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,491 associations by consensus.

RNA5SP250 by BSDC1 expression — LUSC

Explore this box plot interactively →