BSDC1

Across TCGA patient cohorts, BSDC1 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BSDC1-associated genes across cancer lineages are Rab11, ASNS, and C-Raf. Each is linked with BSDC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BSDC1-to-partner and partner-to-BSDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rab11 grouped by BSDC1-low versus BSDC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BSDC1→partner) and Y-score (partner→BSDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rab11 →	-0.157	-3.150	.019	.019	3	2
UCEC	ASNS →	+0.440	+2.321	.009	.034	3	2
UCEC	C-Raf →	+0.199	+2.999	.002	.035	3	2
UCEC	eIF4E →	+0.241	+3.700	.014	.001	3	1
UCEC	MEK1 →	+0.507	+3.459	.002	.005	3	1
UCEC	Caspase-7-cleavedD198 →	+0.987	+3.479	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Rab11 by BSDC1 expression — UCEC

Explore this box plot interactively →