BSCL2

Across TCGA cell cohorts, BSCL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,944 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BSCL2-associated GO terms across cancer lineages are Mitochondrial electron transport, succinate to ubiquinone, GPI anchor metabolic process, and GPI anchor biosynthetic process. Each is linked with BSCL2 in more than 7 cancer types. Because this analysis shows association rather than direction, both BSCL2-to-partner and partner-to-BSCL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, succinate to ubiquinone grouped by BSCL2-low versus BSCL2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BSCL2→partner) and Y-score (partner→BSCL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Mitochondrial electron transport, succinate to ubiquinone →	+0.109	+1.245	<.001	<.001	3	8
LUNG_SCLC	GPI anchor metabolic process →	+0.078	+1.246	.001	.002	3	8
LUNG_SCLC	GPI anchor biosynthetic process →	+0.078	+1.246	.001	.002	3	8
LUNG_SCLC	GPI anchored protein biosynthesis →	+0.078	+1.246	.001	.002	3	8
OVARY	Lipid droplet organization →	+0.082	+1.461	<.001	<.001	3	7
CNS	Response to unfolded protein →	+0.089	+1.051	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,944 associations by consensus.

Mitochondrial electron transport, succinate to ubiquinone by BSCL2 expression — LUNG_SCLC

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